The Relationship Between Hepatic Lipase Gene Variant and Advanced Age-Related Macular Degeneration
نویسندگان
چکیده
منابع مشابه
aspirin and age related macular degeneration; the possible relationship
800x600 age-related macular degeneration (amd) is becoming the leading cause of blindness in developed countries. the exact etiology and pathophysiology of amd is still unclear. a number of risk factors of amd have been recognized, such as cigarette smoking, a family history of amd and being caucasian. on the other hand, aspirin is a widespread medication, which is thought to be associated with...
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PURPOSE The purpose of this study was to examine the relationships between choriocapillaris (CC) and retinal pigment epithelial changes in age-related macular degeneration (AMD). Morphologic changes in the retinal pigment epithelium (RPE)/choriocapillaris complex were quantified in dry and wet forms of AMD, and the results were compared with those in aged control eyes without maculopathy. MET...
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age-related macular degeneration (amd) is the leading cause of blindness in old subjects. it is a multifactorial disease with both environmental and genetic factors playing some role in its pathogenesis. similar to many other genetic diseases, the inheritance pattern of amd does not fit into simple mendelian rules. these diseases are caused by the presence of multiple genetic factors and are ca...
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Background & Aims: To investigate the association of CFI p.Gly119Arg polymorphism with Age-related macular degeneration (AMD). Materials & Methods: In this case-control study, the association of p.Gly119Arg polymorphism in CFI gene was investigated in 65 patients suffering from AMD and150 healthy age, sex and ethnicity matched unrelated people as control group. Both of the case and cont...
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Stargardt disease is a recessively inherited degeneration of the macula of the retina arising in youth (usually in teenagers and young adults) that is caused by defects in the ABCR gene (1). Rando Allikmets et al. investigate (2) the idea that heterozygote carriers of ABCR mutations might develop age-related macular degeneration (AMD) late in life. We wish to point out methodological deficienci...
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ژورنال
عنوان ژورنال: JAMA Ophthalmology
سال: 2014
ISSN: 2168-6165
DOI: 10.1001/jamaophthalmol.2014.1752